The future of oral care starts here. Let’s formulate it together!
We are specialized in oral care formulation, helping brands create, improve, and scale high‑performance oral care products.
How can we help you?
Formulation
We formulate — or reformulate — oral care products across every major category: toothpaste, mouthwash, gels, enamel strengtheners, whitening systems, and more.
Have an idea for a new product category? We’ve developed entirely new concepts for companies around the world, including microbiome‑aligned formulations that support a healthier oral ecosystem.
Already have a product? We upgrade it with natural ingredients, remineralization strategies, and next‑generation technologies.
Troubleshooting & Upscaling
We solve formulation challenges at any stage — from ingredient replacement to improving stability, texture, and performance.
Need to upscale? We support pilot‑to‑factory transitions, identify suitable private‑label manufacturers, and guide packaging choices that fit your formula and market.
Whether you’re stuck, scaling, or optimizing, we make sure your product works the way it should.
Whitening
Whitening regulations differ by country, and hydrogen peroxide limits can be complex.
We’ve formulated many of today’s effective and legally compliant whitening gels, tailored to regional requirements.
Whether you need to fix an existing product or develop a new whitening system for your market, we ensure safety, compliance, and strong performance.
Creating Your Own Oral Care Brand
From idea to shelf‑ready product — we build your brand with you.
Whether you’re launching your first oral care line or expanding an existing portfolio, we guide you through every step of creating a high‑performance, compliant, and commercially viable brand. We help you define your product architecture, select the right actives, and build formulas that match your positioning — natural, clinical, microbiome‑friendly, whitening‑focused, or premium science‑driven.
Need manufacturing? We connect you with trusted private‑label and contract manufacturers, prepare technical documentation, and ensure your formula is ready for scale. Need differentiation? We design unique concepts, ingredient stories, and performance claims that stand out in a crowded market.
From concept to formulation, from samples to production — we help you create an oral care brand built on real science and real performance.
What kind of oral care brand are you looking to build?
Blog 1: Fluoride
What if remineralization of the teeth can also be done without fluoride?
Fluoride has been the gold standard in dentistry for decades. But safety discussions and consumer preferences are shifting . New remineralization-focused technologies are stepping into the spotlight, like hydroxyapatite, the same mineral your enamel is made of.
Originally developed by NASA for astronauts who couldn’t spit in space. Sangi Co. Ltd brought it to consumers in their toothpaste. Hydroxyapatite was advanced further by Fluidinova, whose nano‑hydroxyapatite (nanoXIM®) has been evaluated as safe by the SCCS for use in toothpaste and mouthrinses.
Kalichem expanded the possibilities of hydroxyapatite with their Kalident® line, including hydroxyapatite enriched with magnesium.
With so many suppliers, particle sizes, and performance claims, choosing the right system can quickly become a jungle.
That’s where Nequia comes in. We help brands navigate the science, select the right grade, and build formulations designed for remineralization performance.
So what do you think: Will fluoride remain the standard, or is hydroxyapatite becoming the new hero of oral care?
The future of oral care starts here. Let’s formulate it together.
Blog 2: Thickeners
What is the best thickener for a toothpaste?
A toothpaste is a blend of many components: actives, solvents, abrasives, preservatives, surfactants, and of course, thickeners.
There is no perfect thickener for all toothpaste.
Each thickener behaves differently and there are many thickeners on the market: xanthan gum, carboxymethylcellulose (cmc), smectite clay like LAPONITE, acryl acid polymers such as Carbopol® and many more. They all give their own type of gel structure, flow and stickiness.
Actives can diminish the thickening effect of the thickeners, but abrasives can increase the viscosity. The final feel of how the paste comes out of the tube and sit on the brush depends full on the total system and not just one ingredient.
Finding the right rheology is a balancing act, where Nequia can help. We help brands selecting the right thickeners for your formulation.
Which thickeners do you prefer working with?
The future of oral care starts here. Let’s formulate it together!
Blog 3: SLS
Which mild surfactant would you use for toothpaste?
There is a huge variety of surfactants for toothpaste and mouthwash. The most commonly used is sodium lauryl sulfate (SLS). It works well, but it can be harsh for the oral mucosa and the oral microbiome, depending on your formulation.
That’s why brands look at milder alternatives. Biosurfactants can be especially interesting: they tend to be gentler and can bring additional functional benefits, depending on the type.
A type of biosurfactants is the glycolipid family, which includes rhamnolipids and sophorolipids.
In these space there are several players like Evonik with Rheance One, Holiferm and BioReNuva.
But changing to biosurfactants is not plug and play. Each behaves differently, so your formulation needs to be adjusted to get the foam, clarity, stability and mouthfeel you want.
Here is where Nequia can help. We help brands selecting the right surfactant(s) for your formulation. Also we can look into helping to make your formulation less harsh for the oral microbiome.
Which surfactant do you prefer working with?
The future of oral care starts here. Let’s formulate it together!
About us
Nequia specializes in oral care formulation. Our leadership team — President Matt Spaid and Director Peter Helversteijn — brings more than 15 years of hands‑on experience in developing, improving, and upscaling oral care products. Together, we have created over 40 formulations, filed multiple patents, and supported the production of more than one million products worldwide.